Table 3 Cox proportional hazards analysis of overall survival in patients with complete data for all variables in the validation cohort (n = 142)
Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Age (> 71 vs. ≤ 71) | 1.16 | 0.53–2.54 | 0.71 | – | – | – |
Sex (male vs. female) | 1.46 | 0.65–3.24 | 0.36 | – | – | – |
Smoking history (yes vs. no) | 1.30 | 0.59–2.85 | 0.52 | – | – | – |
Corticosteroid or immunosuppressive agents (yes vs. no) | 0.64 | 0.25–1.59 | 0.33 | 0.62 | 0.25–1.57 | 0.32 |
%FVC (< median vs. ≥ median) | 3.35 | 1.40–8.04 | *0.0068 | – | – | – |
%DLco (< median vs. ≥ median) | 3.00 | 1.25–7.19 | *0.014 | – | – | – |
ILD-GAP index (> 2 vs. ≤ 2) | 3.00 | 1.37–6.59 | *0.0062 | 3.00 | 1.36–6.61 | *0.0063 |
CCL17 (> 418 vs. ≤ 418) | 2.22 | 1.00–4.96 | 0.051 | 2.42 | 1.08–5.44 | *0.032 |