Table 3 Unadjusted outcomes of relevant clinical status

Progressive disease (Yes)

n = 204

96 (47)

n = 93

62 (67)

n = 111

34 (31)

< 0.001^χ

4.53

2.51–8.18

FVC (%) change

n = 204

-2.07 ± 12.1

n = 95

-3.24 ± 15.9

n = 109

-1.05 ± 7.08

0.116^u

-

-

DLCO (%) change

n = 198

-2.55 ± 10.6

n = 92

-2.70 ± 12.0

n = 106

-2.00 ± 9.26

0.524^u

-

-

FVC (L) change

n = 204

-0.095 ± 0.31

n = 95

-0.12 ± 0.39

n = 109

-0.072 ± 0.22

0.134^u

-

-

Lung transplantation (Yes)

n = 218

33 (15)

n = 104

22 (21)

n = 114

11 (10)

0.018^χ

2.51

1.15–5.48

Death (Yes)

n = 216

43 (20)

n = 104

24 (23)

n = 112

19 (17)

0.261^χ

1.47

0.75–2.88

Radiological Worsening 2y

 Yes

 No

n = 207

69 (33)

138 (67)

n = 94

45 (48)

49 (52)

n = 113

24 (21)

89 (79)

< 0.001^X

3.41

1.86–6.24