Fig. 2
From: A genome-wide association study of adults with community-acquired pneumonia
Manhattan plot of the genome-wide association study results for adult CAP. The x-axis represents the chromosome positions while the y-axis represents the transformed p-values (–log10 [p-value]) obtained by logistic regression models using EPACTS v.3.2.6. Each point represents the result of a genetic variant analyzed. The variants that were deemed to be significantly associated with CAP exceed the significance threshold set at p-value = 5.0 × 10− 8, represented by the horizontal line. The inset on the top right represents the Quantile-Quantile (QQ) plot comparing the observed -log10 (p-values) from the GWAS analysis on the y-axis with the expected p-values under the null hypothesis on the x-axis. The genomic inflation factor (λ = 1.04) did not suggest inflation of the results obtained